Patients with recurrence of glioma need to be evaluated and treated with surgery, radiotherapy, chemotherapy and other treatments according to their condition. Glioma is a malignant tumor that is prone to recurrence. When recurrence occurs, the grade of the glioma is first evaluated, and the grade of recurrence is often higher than the grade of the glioma first detected, and the patient’s condition allows for another surgical treatment. Surgical resection may be incomplete, so after surgical resection of the recurrent tumor, radiotherapy can be performed, and stereotactic radiation can be considered as a minor treatment, and chemotherapy can be performed if necessary. In the process of radiotherapy or chemotherapy, pay attention to observe whether there is bone marrow suppression and adverse reactions in the digestive tract. For patients with recurrent glioma, it is recommended to consult the neurosurgery department of a regular hospital.