Voriconazole twice a day to take a few hours between serving variable, generally need to be 8~12 hours apart, voriconazole has adverse reactions, contraindications, the use of medication need to be guided by a doctor. If you take voriconazole twice a day, you can arrange to take the time in the morning and evening, the interval is not certain, in order to give voriconazole to leave a certain amount of time for the efficacy of voriconazole to play time, the two times to take voriconazole interval time should be about 8 to 12 hours. Voriconazole is a kind of antibiotic, suitable for fungal infection treatment, there may be headache, insomnia, diarrhea, nausea, vomiting, rash and other adverse reactions after using the drug, it is prohibited for those who are allergic to the components of voriconazole, and it is prohibited for those who are taking CYP3A4 substrate, sirolimus, ergot alkaloids and other drugs. Taking voriconazole should be guided by a professional doctor and should not be abused.