Mild interstitial changes in both lungs is the terminology used when imaging the lungs and can be due to infectious or non-infectious factors. 1. Mild interstitial changes in both lungs may be reported during a lung X-ray or CT examination. The term “mild interstitial changes” is used when mild interstitial fibrosis, interstitial edema, or fibrous hyperplasia is seen in both lungs of the patient during the imaging examination. 2. It can be caused by infectious or non-infectious factors, common infectious factors are bacteria, viruses, mycoplasma, etc., and infections can spread to the interstitium of the lungs and cause this kind of manifestation; non-infectious factors include long term smoking, pneumoconiosis, radiation pneumonitis, rheumatic immunity disease, etc.. Non-infectious factors include long-term smoking, pneumoconiosis, radiation pneumonitis, rheumatoid immune disease, etc. It is recommended to consult a doctor for scientific treatment under the guidance of a doctor.