Soreness of the back of the hand may be caused by physiological factors, but also may be caused by fasciitis, acute injury, cervical spondylosis and other factors. 1. Physiological factors: prolonged strenuous exercise, such as basketball or heavy physical labor, may lead to excessive fatigue of the muscles of the back of the hand, will cause arm pain, is a physiological phenomenon. 2. Fasciitis: the back of the hand for a long time cold, or suffered an injury, may induce aseptic inflammation of the fascia, inflammatory substances increase, will cause arm pain. 3. Acute injury: such as prolonged compression or external blow, resulting in soft tissue damage to the back of the hand, there will be soreness, may also be accompanied by redness of the skin, localized swelling and other symptoms. 4. Cervical spondylosis: such as neurogenic cervical spondylosis, prolonged improper posture, resulting in nerve root compression, will cause arm soreness, may also be accompanied by upper extremity radiating pain, upper extremity numbness and other symptoms. The back of the hand is sore, the symptoms are more obvious, exclude the physiological factors, it is recommended to go to the hospital in time, under the guidance of the doctor standardized treatment.