Frequent leg pain and weakness may be caused by lumbar intervertebral disc herniation, lower extremity arterial occlusion, lower extremity venous reflux obstruction, etc., which needs to be analyzed specifically. 1. Lumbar intervertebral disc herniation: when lumbar spinal disc herniation compresses the nerves of the lower limbs, leg soreness and weakness of the lower limbs may occur, which can often be accompanied by numbness, and its main manifestation is the abnormality of one side of the limbs. 2. Lower extremity arterial occlusion: when the patient has diabetes, hypertension or likes to smoke a lot, it is easy to induce the occurrence of lower extremity arterial plaques, which will lead to lower extremity muscle circulation disorders, and there may be leg soreness, weakness, and intermittent claudication may occur. 3. Lower extremity venous return obstruction: when the patient has lower extremity varicose veins, deep vein thrombosis or venous valve closure insufficiency, it will cause venous return abnormality, which may cause frequent leg soreness and fatigue. When there is frequent leg soreness and fatigue, you should go to the hospital in time and find out the cause under the doctor’s guidance and then treat it actively to avoid delaying the condition.