Inflammatory granulation tissue in the bladder is a manifestation of chronic inflammation in the bladder, which can cause obvious urinary abnormalities and localized pain and discomfort. Chronic inflammation in the bladder can lead to the formation of local granulation tissue; the corresponding lesion is mainly manifested as a soft tissue bulge in the bladder, accompanied by obvious symptoms of bladder irritation, such as urinary frequency, urgency, urinary pain, and partly due to local surface ulceration, hematuria will occur, and the pathological examination is mainly for the epithelial tissue hyperplasia and inflammatory cell infiltration. Inflammatory granulation tissue in the bladder can be cleaned up locally by cystoscopy, and if necessary, the bladder can be irrigated with antibiotics (cefixime, etc.), which can help to promote the repair of inflammation. The presence of obvious urinary abnormalities, or even urinary tract obstruction, requires prompt medical observation and standardized treatment under the guidance of the clinician.