Soreness in the trapezius muscle should be relieved in different ways depending on the cause, which may be physiologic or pathologic, with common pathologic causes such as fasciitis and osteochondritis dissecans. Specific relief methods include physical therapy, drug therapy and surgical treatment. 1. Physiological: Soreness of the trapezius muscle during sleep may be due to long-term work, if the soreness is not too serious, adequate rest can be relieved. You can also massage and apply hot packs to the local location to relax the trapezius muscle and speed up the recovery. 2. Fasciitis: Oral non-steroidal anti-inflammatory drugs such as ibuprofen can be taken to play the role of anti-inflammatory and analgesic. If conservative treatment is not effective, soft tissue release surgery can be performed to reduce muscle soreness. 3. Osteochondritis Dissecans: Osteochondritis Dissecans can be treated with oral non-steroidal anti-inflammatory drugs such as ibuprofen, etc. In severe cases, debridement and drainage surgery is needed to promote wound healing. Therefore, it is recommended that the patients concerned should consult a doctor in time to find out the cause of the disease and follow the doctor’s advice for treatment. The use of drugs should be in accordance with medical advice.