The occurrence of villous changes in the mucosa of the gastric angle is generally considered to be chronic inflammation of the stomach, which is altered when intestinalization occurs. Chorioallantoic changes in the stomach are not cancerous, and may be induced by alcohol stimulation, drug stimulation, bacterial infection as well as Helicobacter pylori infection. It is recommended to go to a regular hospital to receive carbon 13 and carbon 14 breath test for a clear diagnosis, and it is necessary to undergo gastroscopy to understand the condition of the stomach. If patients take drugs for a long time, especially on an empty stomach, it will lead to gastrointestinal mucosa being stimulated and cause gastric lesions. Alcohol content will lead to changes in the mucous membrane of the stomach due to adverse stimulation. It is recommended that patients go to regular hospitals to receive further examination, according to the results of the examination, under the guidance of specialists to actively receive treatment, to avoid affecting the health of the body.