Portal vein cancer thrombus can be treated by surgery, transcatheter arterial chemoembolization (TACE), and double cannulation chemotherapy of hepatic artery and portal vein. Portal vein cancer embolism refers to the invasion of liver cancer from the edge to the center of the liver into the portal vein in the liver, and it can also invade the left and right branches of the portal vein, and even the main trunk of the portal vein and the superior mesenteric vein. 1. Surgical treatment: Hepatocellular carcinoma (HCC) is mainly treated by resection of the thrombosed portal vein or portal vein incision to remove the thrombus at the same time. After surgery, arterial chemoembolization, ultrasound intervention, biotherapy and other comprehensive treatments are supplemented to prolong the survival time and improve the quality of life of patients. 2. Transcatheter arterial chemoembolization (TACE): the efficacy of TACE on liver cancer has been recognized. Surgery and pathology have confirmed that TACE can not only lead to tumor necrosis, but also to portal vein cancer thrombus necrosis. 3. Double cannulation chemotherapy of hepatic artery and portal vein: blocking hepatic artery and portal vein at the same time only causes slight damage to the liver, which increases the rate of necrosis of the main tumor from 23.3% in hepatic artery embolization to 64.7%. Patients are advised to live a regular life and develop good habits. Strengthen physical exercise, enhance physical fitness and immunity, combine work and rest, do not overwork.