Nipple pain in menopausal women may be caused by breast hyperplasia, breast cancer, hormonal abnormalities and other reasons. 1. Mammary gland hyperplasia: Mammary gland hyperplasia is mainly caused by endocrine function disorders of the body, and age, pregnancy and childbearing history, history of contraceptive pills, dietary structure, physiological factors, etc. can induce mammary gland hyperplasia, which can manifest the symptoms of cyclic pain in the breasts, breast lumps and so on. 2. Breast cancer: Breast cancer is one of the common malignant tumors in women, which can be manifested as nipple or areola abnormality, nipple overflow, painless breast lumps and other symptoms, and for patients with eczema-like breast cancer, nipple pain will occur. 3. Hormonal abnormality: the hormone level in the body will continue to decline and become chaotic after menopause, which will stimulate the expansion of blood vessels in the breasts and may cause nipple pain. When this condition occurs, it is recommended to go to the hospital for examination, to clarify the cause of the disease and timely symptomatic treatment.