The normal range for weight loss on metformin is between 1 and 3 pounds, but this may vary from patient to patient. Metformin has been shown to have some weight loss effects when used in the treatment of patients with type 2 diabetes. Studies have shown that after 16 weeks of metformin monotherapy in newly diagnosed type 2 diabetic patients, normal-sized, overweight, and obese patients lost 1.47 kg, 2.81 kg, and 2.92 kg, respectively. Metformin is a biguanide hypoglycemic drug, which can reduce hepatic glucose synthesis and intestinal glucose absorption, help diabetic patients make full use of endogenous insulin, and lower fasting fasting as well as postprandial 2 hyperglycemia. It is mainly used for the treatment of patients with type 2 diabetes mellitus who are not satisfied with dietary control and physical exercise alone. It should be noted that those who are allergic to metformin, those with renal disease, those with intravascular injection of iodinated contrast medium, and those with acute and chronic metabolic acidosis are prohibited from using it. Patients may experience adverse symptoms such as diarrhea, abdominal pain and loss of appetite after taking it. It is recommended that patients use Metformin under the guidance of a doctor, and if patients continue to lose weight after use, it is best to go to the hospital in time.