Small doses of prednisone can be taken during preparation for pregnancy if the condition requires it. Prednisone belongs to the group of hormonal drugs that are mainly used to treat immune disorders. The first trimester of pregnancy is the prime time for embryonic development, especially in the early stages of pregnancy. Taking a large dose of prednisone may cause the embryo to develop abnormally or even miscarry. If you need to take medication because of illness, you can take a small dose of prednisone orally under the guidance of your doctor. Small doses of prednisone will not cause teratogenic effects on the fetus. If you do not know whether you can take certain foods or medications during your pregnancy, it is recommended that you consult a specialist, and also pay attention to regular gynecological examinations, so that problems can be detected and dealt with at any time.