The “two valves” should be the mitral valve, mitral valve replacement surgery, if atrial fibrillation is feasible drug therapy or atrial fibrillation radiofrequency ablation therapy. 1. Drug therapy: amiodarone or propafenone can be applied to change the heart rhythm, terminate atrial fibrillation episodes to restore sinus rhythm, and follow the doctor’s instructions to take drugs to maintain the heart rhythm. If the heart rhythm can not be restored, the application of metoprolol, bisoprolol, digoxin and other drugs to control the ventricular rate, to prevent tachycardia. At the same time, follow the doctor’s instructions, if necessary, apply anticoagulant drugs to prevent thrombosis. 2. Radiofrequency ablation therapy: If atrial fibrillation is not well controlled after drug treatment, radiofrequency ablation therapy can be considered. Termination of atrial fibrillation episodes. After mitral valve replacement surgery, attention should be paid to monitoring the heart rate, blood pressure, pulse changes, review the electrocardiogram, if there is any abnormality should be timely treatment. After discharge from the hospital, you should rest more, avoid strenuous exercise, and regularly review the cardiac ultrasound.