HPV53 is the suspected high-risk type. There are more than 200 known HPV types, and only about 40 are associated with genital tract infections. There are 12 common high-risk HPV types: 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59; and 8 suspected high-risk HPV types: 26, 53, 66, 67, 68, 70, 73, 82. These types of HPV infection are associated with cervical cancer and high-grade squamous intraepithelial lesions of the vulva, vagina and cervix. If the test is positive for HPV53, cervical TCT is preferred to rule out cervical intraepithelial neoplasia and cervical cancer. 1. If the TCT test is negative, then it is simple HPV infection. For young people with strong resistance, usually no special treatment is needed, and they can recover from HPV infection on their own, and follow the doctor’s instructions to do regular checkups; for people with weak resistance, they need to follow the doctor’s instructions to choose XinFuNing, Rebeson and so on to carry on the symptomatic medication, or to carry on the physical therapy such as laser, microwave, freezing and so on. 2. If the TCT test is positive, surgical treatment, such as cervical conization, should be considered according to the patient’s condition. In addition, due to the infectious nature of high-risk HPV, it is recommended that sexual partners should be investigated and treated together for early detection and timely treatment, and avoid coitus during the treatment period to minimize the spread of the virus.