Multi-systemic symptoms may appear in the late stage of uremia, mainly manifested as edema, heart failure, shortness of breath, lack of appetite, nausea and vomiting, anemia, etc.
1. Water and electrolyte metabolism disorders: including metabolic acidosis, edema caused by water-sodium retention, potassium metabolism disorders, calcium-phosphorus metabolism disorders, magnesium metabolism disorders and so on.
2. Cardiovascular system manifestations: hypertension and left ventricular hypertrophy, heart failure, uremic cardiomyopathy, pericardial effusion and so on.
3. Respiratory system manifestations: shortness of breath, pulmonary edema, pleural effusion, etc.
4. Gastrointestinal symptoms: lack of appetite, nausea and vomiting, smell of urine in the mouth, etc.
5. Hematological system manifestations: renal anemia, bleeding tendency and thrombosis tendency, etc.
Patients with advanced uremia should go to the hospital in time and receive standardized treatment under the guidance of professional physicians.