Vitiligo on the buttocks, can be related to genetic, neuropsychiatric factors or autoimmune response and other reasons. 1. genetic factors: vitiligo is an acquired pigment loss skin disease, can be seen in the head and face or abdomen, lumbosacral and other parts, the occurrence of vitiligo can have a family history, although not found obvious genetic pattern, but it may be a polygenic genetic disease, with susceptibility and genetic heterogeneity. 2. neuropsychiatric factors: some people in the mental stimulation, due to neuronal mediators affect melanin, can lead to vitiligo. 3. autoimmune reaction: often accompanied by other autoimmune diseases such as anemia or thyroid disease, most patients have anti-melanocyte antigen autoantibodies in the serum. After the diagnosis of vitiligo, it is recommended to consult a doctor in time, and should follow the doctor’s instructions to choose the appropriate treatment and medication, in order to control the development of the disease, repair the internal environment and promote the formation of melanin.