The occurrence of vitiligo in children may be related to heredity, autoimmune system diseases, neurochemicals and so on. 1. heredity: melanin is produced by melanocytes, if melanocytes are destroyed, it will lead to a reduction in melanin formation, vitiligo, this disease and heredity have a certain relationship, parents who have vitiligo, children with vitiligo have a greater chance of suffering from vitiligo, it is a polygenic disease category. 2. autoimmune disease: vitiligo pathogenesis autoimmune system related, the patient’s blood serum in the presence of anti-melanocyte surface and cytoplasmic antigen antibodies, resulting in the destruction of melanocytes, the reduction of pigment production. 3. Neurochemicals: Segmental vitiligo may be caused by the release of neurochemicals from nerve endings in the skin, which can destroy melanin and reduce melanin production. If diagnosed with vitiligo, it is recommended to standardize the treatment as early as possible to reduce the adverse effects of the disease.