Neurodermatitis, also known as chronic lichen simplex, can be treated by topical medication, oral medication and physical therapy. 1. Topical drug therapy: thin lesions can be applied locally with tacrolimus ointment, hydrocortisone ointment and other drugs, which can help to reduce the itching symptoms of patients. Those with thicker lesions should be treated with encapsulation therapy to enhance the penetration of drugs and prevent the lesions from being scratched. 2. Oral medication: oral loratadine, vitamin C, calcium, etc., together with the application of glutamine and B vitamins, can help anti-allergy and relieve itching symptoms. 3. Physical therapy: phototherapy, medicated baths, mineral baths, etc. can be used for people with extensive skin lesions. Neurodermatitis patients should go to the hospital in a timely manner, under the guidance of the doctor to carry out regular treatment, to avoid further aggravation of the condition. The drugs mentioned above should be used in accordance with medical advice.