Vitiligo on the nose can be treated with medication and physical therapy. 1. medication: for limited vitiligo that involves the face or areas of high risk of skin atrophy, topical calcium-modulated phosphatase inhibitors (such as tacrolimus and pimecrolimus) are preferred, which can inhibit local abnormal immune responses and reduce the destruction of melanocytes by immune cells. The drug can be mildly irritating when used initially, and should be used with caution in the presence of localized infections or tumors. Vitiligo can also be progressed in the doctor’s guidance oral prednisone and other glucocorticoid medication to prevent further development of the disease. 2. physical therapy: narrow-wave ultraviolet irradiation, 308nm laser is often used as a complementary treatment for vitiligo, can promote vitiligo lesions within the activation of T-cell apoptosis, improve the local environment, to create good conditions for the production of melanocytes, is conducive to the recovery of pigmentation. In addition, for the long in the nose, the condition of stable vitiligo patients, can also be used epidermal transplantation treatment. It is recommended that patients with vitiligo on the nose go to the dermatology department of the regular hospital in a timely manner, under the guidance of the doctor’s strict adherence to standardized treatment.