The heavy and prolonged menstruation of 48-year-old women is considered to be related to endocrine dysfunction, uterine fibroids, adenomyosis and so on. 1. Endocrine dysfunction: for 48-year-old women, due to their ovarian function decreasing, so the patient will have irregular ovulation, so irregular menstruation, increased menstrual flow, prolonged menstrual period and other menstrual abnormalities. 2. Uterine fibroids: for women with uterine fibroids, especially submucous fibroids, due to the increase of uterine volume and endometrial area, so the patients will experience discomfort such as heavy menstruation and prolonged menstruation. 3. Adenomyosis: Since the ectopic endometrium is planted in the myometrium, the uterine volume will be limited or persistently enlarged, so the patients will have clinical symptoms such as progressively aggravated dysmenorrhea, heavy menstruation and prolonged menstruation. For 48-year-old women with heavy and prolonged menstruation, it is recommended that they go to the gynecology department of a regular hospital to improve gynecological ultrasound, sex hormones and other related examinations, and then actively treat the disease under the guidance of doctors after clarifying the cause.