How effective is the treatment of cirrhosis with entecavir combined with turtle shell decoction pill?

According to relevant clinical reports and existing clinical studies, entecavir combined with turtle shell decoction pills for the treatment of cirrhosis can effectively treat cirrhosis and improve hepatocellular inflammation and other effects, but this treatment is not explicitly recommended in the guideline treatment.
Entecavir is commonly used in capsules, tablets and dispersible tablets for the treatment of chronic adult hepatitis B with active viral replication, persistent elevation of serum alanine transferase, or active hepatic histological lesions, and the common adverse effects include headache, dizziness, nausea and diarrhea.
Tetrapod Decoction Pill is a proprietary Chinese medicine, which is made of 23 Chinese medicines, including Gui Zhi, Tetrapod (stir-fried), Colla Corii Asini, Tetrapod Gum, Scutellaria Baicalensis, Radix Codonopsis Pilosulae, Peach Kernel, and Dried Ginger, etc. It has the efficacy of softening and dispersing knots, activating blood circulation and removing blood stasis, and the adverse effects of the drug are unclear, and is contraindicated in pregnant women.
Entecavir combined with turtle shell decoction pills for the treatment of hepatitis B cirrhosis can effectively improve liver fibrosis in chronic hepatitis B patients, and at the same time can improve hepatocellular inflammation, but need to be used under the guidance of a doctor, and should not be self-administered, in order to avoid adverse reactions.