Freckles are not necessarily hereditary, but there is a higher chance of inheritance. Clinically, freckles are common pigmented skin diseases, showing yellowish-brown pigmented spots on the skin. It usually develops in children and adolescents, and the lesions gradually become more and more dark with increasing age and ultraviolet radiation. Freckles may be an autosomal dominant skin disease, and the causative gene may be located on chromosome 4. Most people with freckles are associated with hereditary factors and have a tendency of family inheritance. Parents with a history of freckles are more likely to have freckles in their children. Patients who are willing to have freckle treatment are recommended to visit regular hospitals in time and have appropriate treatment under the guidance of specialized doctors.