Twitching sensation in the liver area may be caused by gastrointestinal spasm, hepatitis, cirrhosis and other reasons. 1. Gastrointestinal spasm: gastrointestinal spasm is a syndrome caused by a variety of diseases, mostly caused by eating too much, too hot food, while the abnormal contraction of the stomach and intestines will cause a certain amount of stimulation of the nerves, resulting in neuropathic pain, which can be manifested as a twitching in the liver area, accompanied by pain. 2. Hepatitis: Hepatitis is caused by alcohol, viruses, bacteria and other factors, which will cause some damage to liver cells and enlargement of the liver, thus pulling the liver peritoneum, and liver twitching may occur, accompanied by pain and so on. 3. Cirrhosis: Cirrhosis is a diffuse growth of liver fibers on the basis of extensive necrosis of liver cells, and pseudolobules and regenerative nodules will appear, which will lead to pulling of the liver peritoneum, resulting in liver twitching and pain in the liver area. In addition, if you suffer from liver tumors can also lead to convulsive sensations in the liver area, it is recommended to go to a regular hospital for examination, to clarify the cause of the disease, and to follow the doctor’s instructions for timely treatment.