The yellowing of the soles of the feet in girls may be related to fungal infections, jaundice, keratosis, etc. It should be improved by medication and other methods according to the cause of the disease. 1. Fungal infection: If the patient has a fungal infection on the soles of the feet, it may lead to itchy skin on the soles of the feet, as well as yellowing and other phenomena. It can be treated by local application of miconazole cream, ketoconazole cream, etc. If necessary, it can be combined with oral itraconazole capsules, terbinafine tablets and other drugs. 2. Jaundice hepatitis: For patients with jaundice hepatitis, there will be localized yellowing of the skin, itching and other symptoms, patients will also be accompanied by anorexia, fatigue and other symptoms. Can use polyene phosphatidylcholine, prostaglandin, adenosylmethionine and other hepatoprotective treatment, hepatitis can be controlled, the symptoms of yellowing of the soles of the feet will improve. 3. Keratosis: If the patient’s soles are rubbed by shoes and socks for a long time, it will make the skin keratosis, and the phenomenon of yellowing and thickening will occur. You can soak your feet in warm water to soften and remove the hyperplasia, and try to wear soft shoes and socks. It is recommended that these patients consult a doctor in a timely manner to determine the cause of the disease, and then actively cooperate with the doctor’s treatment, avoid self-medication.