Conscious splenic pain after running is usually not a primary lesion of the spleen and is mostly due to physiologic factors. In addition, it is considered to be a pathologic factor in the presence of primary pathology or the occurrence of trauma. 1. Physiologic factors: pain in the spleen region after running is mostly due to the presence of intestinal distension, i.e., gas. In strenuous exercise can appear intestinal spasm manifestation, causing intestinal distension, pulling the intestinal nerve, appearing pain. Generally, it can be relieved after resting or walking slowly, and it is recommended to warm up sufficiently before running to avoid pain. 2. Pathological factors: if the patient has appendicitis, hyperfunction of liver and spleen, etc., running will lead to the onset of the disease and the emergence of pain, and should stop running in time and go to the hospital immediately for treatment; in addition, if there is a collision of the left side of the abdomen, fall, etc., and then there is a pain in the area of the spleen, accompanied by pale skin color, generalized sweating and other manifestations, it may be a splenic rupture, which requires emergency treatment. Those who are unable to relieve the pain after running or develop conditions such as the above should go to the hospital in time and be treated under the guidance of a doctor.