It is inaccurate to say that if creatinine exceeds 104 μmol/L, the kidney is half broken. It should be judged in the context of individual situation, which may be a healthy state, mild kidney damage or severe kidney damage. Creatinine is mainly filtered by glomeruli in the body and then excreted with urine. So creatinine can also reflect the condition of the kidneys in the body. Creatinine is related to the muscle content in the body, if the muscle content is high, the creatinine value in the body will also increase. If creatinine exceeds 104 μmol/L, it should be judged according to the individual’s condition. If it is a man, this value is normal; if it is a woman, this value is high; if it is a child, it is relatively high. Meanwhile, creatinine can also be elevated in normal people when they eat a large amount of meat for a short period of time or under the condition of strenuous exercise. High creatinine is mainly seen in kidney injury, if acute kidney injury caused by creatinine elevation, after active treatment, generally can be improved, the condition is not serious, if chronic kidney disease, creatinine elevation indicates that the disease has progressed to a certain stage, then creatinine high may suggest that the kidney damage is more serious. Creatinine value is not the only standard to detect kidney function, it is recommended to go to the hospital for detailed testing to determine the condition of the organism’s kidneys.