Aminoglycoside antibiotics have poor antimicrobial activity against genera other than Enterobacteriaceae, Escherichia coli, and Salmonella, and enterococci are highly resistant to these antibiotics and are ineffective against anaerobes. Aminoglycoside antibiotics have strong antibacterial activity against Enterobacteriaceae, Escherichia coli, Salmonella, Serratia, Mycobacterium citri, Mycobacterium tuberculosis, Mycobacterium avium, Shigella, Staphylococcus aureus, Staphylococcus epidermidis strains of bacteria, etc., but have poorer antibacterial activity against bacteria other than these, e.g., Streptococcus. Aminoglycoside antibiotics should not be used if the patient is infected with enterococci or anaerobes, as enterococci are highly resistant to this type of antibiotic, and they are ineffective against anaerobes. It is recommended to use aminoglycoside antibiotics under the guidance of a doctor, if the patient is allergic to aminoglycoside antibiotics, it is contraindicated to use this type of antibiotic treatment. In addition, some patients with aminoglycoside antibiotics may experience ototoxicity, nephrotoxicity and other adverse reactions, such as dizziness, hearing loss, oliguria.