Progesterone capsules have a lot of side effects. A small number of people who take them may experience side effects such as dizziness, fatigue, stomach upset, acne, hirsutism and seborrheic dermatitis, swollen legs, weight gain, breast reduction and flaccidity; shortened or prolonged menstrual cycles, amenorrhea, decreased menstrual flow and irregular bleeding may also occur, but they usually decrease on their own. Progesterone Capsules are clinically used for the treatment of endometriosis. It is contraindicated in pregnant women, lactating women, patients with severe cardiac, hepatic or renal insufficiency, and patients with metabolic or vascular disorders occurring with prior estrogen or progesterone therapy. Progesterone capsules may cause fluid retention and should be closely observed in patients with cardiac or renal insufficiency. Patients need to pay attention to the fact that pregnancy must be excluded before treatment. Liver function should be checked regularly during the medication, and those with mild elevation of aminotransferase can continue the treatment by taking liver-protecting drugs. Strict contraception (prohibit oral contraceptives) during treatment, once pregnant, treatment should be stopped. Patients should not buy and take medicines on their own, it is recommended to go to a regular medical institution and under the guidance of the doctor reasonable use of medicines, in order to avoid serious side effects.