Hypothyroidism is the abbreviation of hypothyroidism, there has not been a clear study on how long a 50-year-old patient with hypothyroidism can live, if standardized with the doctor’s treatment may not affect the survival period, if not standardized treatment may cause mucous edema coma, pericardial effusion and other complications, which will shorten the patient’s survival period. Patients diagnosed with hypothyroidism at the age of 50 can take levothyroxine sodium tablets as prescribed by the doctor to maintain the level of thyroid hormones within the normal range, and should maintain a healthy lifestyle in their daily life, and hypothyroidism in such cases may even be able to avoid affecting the patient’s survival period. However, if the patient does not actively cooperate with the treatment, hypothyroidism can induce heart failure and other serious complications, which will greatly shorten the patient’s survival; improper treatment of hypothyroidism may induce mucous edema coma, which may threaten the patient’s life safety if rescue is not timely, and may even lead to death in a short time. Patients diagnosed with hypothyroidism at the age of 50 should actively cooperate with their doctors to help improve their prognosis.