Thickening of the cyst wall of renal cysts is usually caused by the combination of repeated infections and calcification of the cysts. It is recommended to further define the size of the cysts and the degree of calcification through CT examination, and those with cysts larger than 4cm need to be treated in a timely manner. Patients with renal cysts, if there is a combination of recurrent infections, intracystic hemorrhage, calcification, etc., can cause thickening of the cyst wall, patients can do CT examination to determine the degree of calcification, the size of the cysts and the symptoms of local compression. When the cyst is less than 4cm, the calcification is not serious and needs to be kept under observation. If the cyst is more than 4cm, obvious compression symptoms may appear, or malignant lesion is highly suspected, early examination should be done, and appropriate treatment should be given, if it is benign, minimally invasive interventional therapy can be carried out. Thickening of the cyst wall of renal cysts, it is recommended that patients go to the hospital in a timely manner, through the examination to clarify the specific conditions.