Astringency of the tongue may be burning mouth syndrome or lichen planus, or it may be salivary gland inflammation, which corresponds to the administration of medications such as hexestrol, B complex vitamins, retinoids, antibiotics, and so on. 1. Burning mouth syndrome. Burning mouth syndrome, can feel burning pain in the oral cavity, oral mucosal sensory abnormalities, the general removal of irritating factors can be tried after the use of hexenoestrol, hormonal changes caused by taking progesterone, norethindrone, vitamin deficiency of vitamin B supplementation complex vitamin tablets. 2. Lichen planus. Organism immune diseases can appear flat moss, manifested as oral mucosa roughness, wood astringency, the treatment of the use of vitamin A acid, adrenocorticotropic hormone, hydroxychloroquine and other drugs. 3. Salivary gland inflammation. Mumps can lead to reduced salivary secretion, causing tongue dryness, viral infections caused by inflammation taking antiviral drugs ribavirin, bacterial infections taking antibiotics amoxicillin, metronidazole and other drugs. The specific medication to be taken for tongue astringency, it is recommended to go to the hospital to check the cause of the disease, and then follow the doctor’s instructions to use the medication.