The more you scratch your ankles, the more itchy they get. It may be caused by neurodermatitis, urticaria, eczema and other diseases. 1. Neurodermatitis: Neurodermatitis is a kind of skin disease with intense itching as the main manifestation, which is closely related to psychoneurological factors and occurs in the neck, elbow and other places. Patients scratching the skin when itching symptoms will not be reduced, but will be aggravated by scratching itch. 2. Urticaria: The causes of urticaria include exogenous and endogenous, such as physical stimulation, food, infection and autoimmune, psychoneurological factors. The patient will appear windburn or angioedema, mostly accompanied by itching. If you don’t keep away from the allergens, the more you scratch, the more itchy it is. 3. Eczema: Eczema is a chronic inflammatory itchy skin disease, polymorphic rash, mostly self-conscious itching, can be seen at the ankles. The nerves after scratching will be more sensitive, which will lead to the patient scratching more itchy. There are more reasons for itchy ankles (e.g., insect bite dermatitis, etc.), and patients are advised to seek medical examination for a clear diagnosis.