Sudden swelling and pain in the toes consider gout, onychomycosis, venous thrombosis of the lower extremities and other causes. 1. Gout: mostly caused by eating more purine food and eating more seafood food. Sudden pain, more intense, localized redness and swelling, laboratory tests uric acid is obviously elevated. 2. Inguinitis: due to the toe nail seam at the soft tissue infection pus toes suddenly swollen, red and swollen obviously, need to carry out debridement and drainage. 3. Lower extremity venous thrombosis: due to lower extremity braking or other parts of the thrombus off the lower extremity caused by poor blood return, sudden swelling of the toes, local purple, cold, do lower extremity vascular ultrasound can be clearly diagnosed. Suddenly swollen toes pain may also be due to toe fractures and bone tumors and other diseases, although the probability of occurrence is relatively small, but also to pay attention. Sudden swelling and pain in the toes, you need to go to the hospital for further treatment after a clear diagnosis.