Helicobacter pylori does not usually cause thrombocytopenia. Helicobacter pylori infection may cause chronic gastritis, gastric ulcer and other diseases, the course of the disease is longer, may induce gastric cancer and other diseases, generally does not cause thrombocytopenia. Thrombocytopenia may be caused by hereditary anemia, aplastic anemia, and platelet destruction caused by immune factors, by abnormal platelet distribution and platelet loss. If Helicobacter pylori infection occurs, it is necessary to go to the gastroenterology department for further examination and treatment in time; if there is thrombocytopenia, it is recommended to go to the hematology department of regular hospitals for further examination, to clarify the cause of the disease, and to actively treat it.