The length of time the drain is clamped after bile duct stone surgery should be gradually extended to observe any adverse reactions. If there is no discomfort, the drain can be kept in place until it is removed. During the period of placing the drain after bile duct stone surgery, we should pay attention to observe whether the drain is smooth, record the amount and color of the drainage flow, whether the patient has abdominal pain, fever and other symptoms, and we can consider clamping the drain after 72 hours in general. It should be clamped for 1~2 hours first to observe whether the patient has any discomfort, and then gradually extend the clamping time if there is no discomfort. If there is no abdominal distension, abdominal pain, fever, nausea, or any other discomfort after the drain is clamped, it can be kept clamped until the drain is removed after the examination. During the process of placing the drain for bile duct stones, we should do a good job of patient care, if there are symptoms such as fever, vomiting and abdominal pain, we should inform the doctor in time, and check and deal with it as soon as possible.