When doing painless gastroscopy with general anesthesia, there are generally no sequelae. Some patients may experience sequelae such as dizziness, memory loss and slow reaction due to anesthesia, but the incidence is relatively small. Painless gastroscopy is based on ordinary gastroscopy, general anesthesia for patients to reduce the pain of patients in the examination process. Painless gastroscopy general anesthesia used in anesthesia is usually propofol, propofol in the body’s faster metabolism, the existence of a short period of time, safer for the human body, and the use of a smaller dose, there is generally no sequelae. However, anesthetic has certain inhibitory effect on the central nervous system, some patients are more sensitive to anesthetic, may appear dizziness, nausea, memory loss, slow reaction and rash and other allergic reactions, but the possibility of occurrence is generally small, and after the effect of the drug can usually gradually return to normal. When painless gastroscopy is performed, the doctor should be consulted in advance and the examination should be carried out reasonably under the doctor’s guidance.