Common peroneal nerve injury, drug treatment is mainly symptomatic, can choose analgesic and nutritive nerve class mainly. If the drug treatment is not effective, it is advisable to choose surgical treatment. Common peroneal nerve injury is most commonly seen in car accidents, crush injuries resulting in peroneal nerve injury, patients may have loss of toe extension function, foot drop deformity and other symptoms. For peroneal nerve injury, drug treatment is mainly symptomatic treatment, can follow the doctor’s instructions to give pain medication, such as ibuprofen, acetaminophen, etc., but also can be given to the nutritional nerve drugs, such as vitamin B1, methylcobalamin, and so on. Most peroneal nerve injuries require surgical treatment. Nerve release surgery can be chosen to relieve nerve compression, help blood supply recovery, and improve the nerve growth environment. Patients can also follow the doctor’s advice to choose nerve suture surgery, nerve grafting, etc.. The treatment options for common peroneal nerve injury may also have some individual variability, so it is recommended to consult a professional doctor to choose the right treatment option for yourself. Patients who are treated with medication should follow the doctor’s instructions strictly.