Levofloxacin generally does not cause diastolic blood pressure to rise, it may be caused by hypertension, etc. It is recommended to stop using the drug and go to the hospital for examination. Elevated diastolic blood pressure may be related to hypertension, coronary heart disease and other diseases, it is recommended to go to the hospital to find out the cause of the disease, stop taking levofloxacin, change to other drugs, such as propranolol, hydrochlorothiazide, etc., and the drug should be selected according to the instructions of the doctor. Levofloxacin is mainly used for mild and moderate infections caused by bacteria, such as bronchitis, pneumonia, tonsillitis, acute prostatitis, bacillary dysentery, and postoperative wound infections. It can cause adverse reactions such as hypotension, dizziness and headache, nausea, diarrhea, rash, edema, and abnormalities of hepatic and renal function, but it does not cause an increase in diastolic blood pressure. Levofloxacin is a prescription drug, the use of antibiotics is recommended under the guidance of a doctor, do not self-diagnosis of the medication, so as not to delay the condition.