Clopidogrel in the size of 75 mg/tablet is not recommended to be taken in halves unless specifically medically prescribed, and it is recommended to be taken as a whole tablet. Attention should be paid to contraindications and adverse reactions in the use of the drug. Clopidogrel is mainly used for the prevention of atherosclerotic thrombosis after myocardial infarction, ischemic stroke, and stent placement after interventional procedures. In the medication guide, its daily oral therapeutic dose ranges from 75mg to 300mg, there is no daily use of 37.5mg, and half a tablet is not recommended unless specifically medically prescribed. Meanwhile, if the daily dosage is 75mg, it is not recommended to move the drug apart or crush the drug and take 37.5mg separately each time, which destroys the integrity of the drug’s shape and may affect the drug’s effect. In case of serious adverse reactions such as intracranial hemorrhage, bleeding in the eyes, thrombocytopenia during the use of the drug, it is recommended to consult a doctor in time. The presence of pathologically active bleeding in the organism, severe hepatic impairment, drug allergy prohibits the use of the drug. The drug needs to be used under the guidance of a clinician.