Urethral and anal pain during ejaculation may be caused by prostatitis, urethritis, seminal vesiculitis and so on. 1. prostatitis: the disease is mainly caused by pathogenic infection, irregular sex life, sedentary, alcoholism, spicy diet, etc., the patient may be in the ejaculation of urethral and anal pain, accompanied by urinary urgency, urinary frequency, urethral burning pain and other symptoms. 2. Urethritis: the disease is mainly caused by pathogenic microbial infections, the onset of pathogens and pathogens increase in number, virulence enhancement, autoimmune function decline and other factors related to the patient will ejaculation urethra and anus pain, usually manifested in the urethra itch, painful urination, urethral orifice redness, urethral secretion and other symptoms. 3. Vesiculitis: Vesiculitis is an inflammation of the seminal vesicle glands, which can be categorized into acute vesiculitis and chronic vesiculitis, and the main symptom is hematospermia. At the same time, the patient may also appear to ejaculation urethra and anus pain, accompanied by urinary urgency, urinary pain, urinary frequency and other uncomfortable symptoms. If the urethral and anal pain during ejaculation occurs, it is recommended that the patient go to a regular hospital in time, under the diagnosis of the doctor, according to the patient’s specific condition, active treatment.