Omeprazole one capsule a day may be able to, but one capsule a day is not enough in the treatment of reflux esophagitis, Droe-Ayer syndrome, and H. pylori eradication therapy. Specific should be judged according to the patient’s condition. Patients need to strictly follow the doctor’s instructions for rational use of medication. Omeprazole can be used to treat duodenal ulcer, stress ulcer, gastric ulcer, reflux esophagitis and Drexel-Ayer syndrome. Most of its specifications are 20mg, patients need to take the drug orally, not chewing. Generally, the drug is used for the treatment of peptic ulcer, need to take 1~2 times a day, each time 20mg (1 capsule), if the patient’s condition is relatively mild, 1 capsule a day is enough. If the drug is used to treat reflux esophagitis, 20-60mg (1-3 capsules) should be taken 1~2 times a day, so 1 capsule a day is not enough. When eradicating H. pylori, 20mg twice a day is also needed. For patients with Zuo-Ai syndrome, the drug should be taken once a day, 60mg (3 capsules) each time, in which case 1 capsule a day is not enough, and the patient needs to adjust the dosage according to the condition of the doctor’s advice. The drug should be used under the guidance of a professional physician, and should not be used on its own.