An AST/ATL ratio greater than 2 may be due to viral liver disease, non-viral liver disease, cirrhosis and other diseases, suggesting abnormal liver function.
1. Viral liver disease: acute viral hepatitis is severe, the beginning of the course of the disease can be a significant increase in glutamic oxaloacetic aminotransferase, glutamic oxaloacetic aminotransferase/glutamic oxaloacetic aminotransferase ratio may be greater than 2; chronic viral hepatitis into the active stage, the ratio can also be greater than 2.
2. Non-viral liver disease: the ratio of AST/ATP is greater than 2. It can also be seen in non-viral liver diseases such as alcoholic liver disease, drug hepatitis, fatty liver, hepatocellular carcinoma, etc., the aminotransferase is mildly elevated or normal, and the rise of AST is more obvious.
3. Cirrhosis: aminotransferase activity depends on the degree of progressive necrosis of hepatocytes. In end-stage cirrhosis, aminotransferase activity is normal or reduced, and the ratio of glutamic/glutamic/cumulative aminotransferase is greater than two.
When the ratio of AST and ALT is greater than 2, it suggests that liver function is impaired, and it is recommended to go to the hospital for comprehensive examination and standardized treatment in accordance with the doctor’s instructions.