It is possible to be infertile with a high antiphosphatidylserine igm. High anticardiolipin igm antibodies can cause infertility. Anti-cardiolipin antibodies are autoantibodies that target cardiolipin as a target antigen, mainly to endothelial cells and platelets. Anti-cardiolipin antibodies are a signature antibody of the antiphospholipid antibody syndrome, which may affect the endothelial cells of the placental blood vessels, inducing thrombosis of the placenta, which in turn leads to adverse effects on the blood circulation of the fetus, causing habitual abortion and infertility. After the diagnosis of high anticardiolipin antibody igm is confirmed, it can be treated by taking thrombolytic drugs, such as alteplase and urokinase, etc. It can also be injected with sodium heparin. It can also be treated with injections of sodium heparin. In addition, the application of the above drugs have certain risks, it is recommended that patients need to take under the guidance of a specialist.