Psoriasis can be treated with topical medications such as glucocorticoid creams, retinoids, calcium-modulated phosphatase inhibitors, and vitamin D3 derivatives. 1. Glucocorticoid cream: common such as tretinoin cream, dexamethasone acetate cream, etc., the drug needs to be standardized under the guidance of a doctor, do not use long-term use, long-term use or stopping the drug, there may be adverse reactions. 2. Vitamin A acid drugs: common such as tazarotene, etc., the drug can appear skin burning sensation, irritation and other adverse reactions, so it is best to be used in conjunction with glucocorticoid creams to reduce stimulation and enhance the efficacy. At the same time, the drug can be absorbed through the skin, so pediatric patients need to be regulated under the guidance of the doctor. 3. Calcium-modulated phosphatase inhibitors: common such as tacrolimus, pimecrolimus, etc., commonly used in the treatment of facial psoriasis, often used in combination with glucocorticosteroids or sequential use of glucocorticosteroids to reduce glucocorticosteroid-induced skin atrophy, hirsutism and other adverse effects. 4. Vitamin D3 derivatives: common such as capotriol, often used in combination with glucocorticoids or alternately, can enhance the efficacy and reduce the adverse effects of the latter. The drug can appear burning sensation, pruritus, skin irritation, tingling sensation and other adverse reactions. In addition, topical creams for psoriasis include emollients, compounding agents, keratin-enabling agents, keratolytic agents, dithranol, anti-human IL-8 monoclonal antibody cream, and other drugs. All of the above drugs should be used under the guidance of a doctor, allergic to the drug components are prohibited, if there is any discomfort during the use of the drug, you need to immediately stop the drug and wash and go to the hospital.