Whether or not 100-200 μmol/L creatinine is important depends mainly on the cause of the elevation. If creatinine is elevated due to physiological reasons or acute kidney injury, creatinine may return to normal after removing the influencing factors, and it usually does not matter at this time. If the creatinine is elevated due to chronic kidney disease, with the progress of the disease, it may develop into uremia, which is relatively serious. Normal serum creatinine is between 53~106μmol/L for men and 44~97μmol/L for women. A blood creatinine of 100 to 200 μmol/L is considered mildly elevated. Some patients with elevated creatinine may be due to the patient’s own high muscle content, or usually eat more meat caused by more exercise, if the urine routine and urinary system ultrasound and other related tests are not abnormal, improve the lifestyle, creatinine may return to normal, such cases usually do not matter. If the patient has acute kidney injury due to various reasons, the blood creatinine increases, after correcting the reversible causes, the creatinine may recover gradually, this usually does not matter. If chronic kidney disease causes elevated creatinine, with the progress of the disease, it may develop into uremia, which is relatively serious. If patients find elevated creatinine, it is recommended to go to regular hospitals in time, under the guidance of the doctor to give targeted treatment or therapy.