Pain after blowing air-conditioning on the hand may be associated with muscle vasoconstriction, nerve edema, tenosynovitis, and so on. 1. Muscle vasoconstriction: when blowing air conditioning on the hand, due to the stimulation of cold air, it can lead to the contraction of the muscles and blood vessels of the hand, causing ischemia and spasm of the tissues, which will lead to the symptoms of pain in the hand. 2. Nerve edema: cold air stimulation can induce acute edema of the nerves and other conditions, so that the hand pain symptoms. 3. Tenosynovitis: when the patient’s hand itself has tenosynovitis, blowing air conditioning can lead to an acute attack of tenosynovitis, making the hand pain symptoms. There can be many reasons for pain after blowing air conditioning, it is recommended to go to the hospital in time to improve the relevant examination for early treatment.