The normal value of large platelets is between 8 and 16%. Large platelets are platelets that are relatively large in size and diameter, and are one of the main components that maintain normal platelet function. When the value of large platelets is too high or too low, it indicates that there is some problem with the platelets, which may affect the normal hemostatic function. 1. The value of large platelets is lower than 8%, which is commonly found in diseases leading to hematopoietic failure, such as aplastic anemia, leukemia, etc. In this case, other relevant examinations should be completed promptly. At this time, other relevant examinations should be completed in time to clarify the diagnosis for appropriate treatment. 2. The value of large platelets is higher than 16%, indicating that the peripheral blood platelets are excessively damaged, but the bone marrow hematopoietic function is normal. This condition is common in autoimmune disease, immune thrombocytopenia and so on. At this time, detailed examination should also be conducted to clarify the diagnosis and receive targeted treatment, such as oral prednisone. Attention should be paid to the following: regular review should be conducted in the hospital to assess the effect of the treatment, and if there is any discomfort, timely medical attention should be sought, and medications should be used under the guidance of a physician.