Rejection of threads is mostly seen as a reaction to silk threads. Whether or not surgery is required for thread removal depends largely on the patient’s condition. Superficial skin sutures usually do not require surgery, and can be removed directly, while deeper sites need to be given debridement. 1. Superficial threads: For superficial skin sutures, surgery is generally not required, and can be removed for threads that show rejection reactions. For patients with short suture time and still not healed, absorbable threads can be replaced and re-sutured, while those with infected and suppurating wounds do not need to be re-sutured and should be given antiseptic and medication change treatment until complete healing. 2. Deep threads: For the deeper location of the internal wound threads in the presence of rejection, there is often a recurrent accumulation of fluid, pus, and even redness, swelling, heat and pain typical of the inflammatory reaction. It is necessary to perform a debridement, open the wound and completely remove all the rejected threads, remove the internal fluid and pus, re-sew with absorbable sutures, and place drainage strips if necessary. It is recommended to go to the hospital for a complete set of auxiliary tests to clarify the condition and to have the appropriate treatment given by a specialized physician.