The appearance of seasonal hands with small blisters, the possible causes of ringworm, sweat herpes, etc., need to be treated according to the cause of the symptomatic treatment, usually using drug therapy. 1. Ringworm: caused by fungal infections, treatment should use antifungal drugs, such as topical ketoconazole, econazole, terbinafine and so on. If the blister type should be used less irritating creams, water. Impregnated vesicular type should be given 3% boric acid solution, 0.1 isacridine, etc. for wet compresses. When the exudation is reduced, then topical antifungal ointment should be used. 2. Sweat herpes: a special type of eczema. It is usually treated with glucocorticoids, such as topical dexamethasone and halometasone. In addition, calcineurin phosphatase inhibitors such as tacrolimus ointment, pimecrolimus ointment, etc. also have better efficacy. If small seasonal blisters appear on your hands, do not use medication on your own, you need to see a doctor as soon as possible and follow the doctor’s instructions.