The main symptoms of patients with duodenal ulcer are pain and dyspeptic symptoms such as warmth and acid reflux, while other manifestations such as weight loss and anemia are seen. Duodenal ulcer is the most frequent type of peptic ulcer, referring to the inflammatory defect that occurs in the mucosa of the duodenum, usually associated with the gastric acid and digestive action of gastric juices, and the lesion penetrates into the muscular layer of the mucous membrane or reaches deeper levels. The main symptoms of duodenal ulcer patients are as follows: 1. Pain: The typical symptom is epigastric pain, the nature of which may be dull, burning, swelling, sharp pain, hunger-like discomfort. Chronic process, up to several years or more than 10 years, recurrent or cyclic episodes, episodes can be weeks or months, episodes of seasonal, typical of those who occur in seasonal changes, such as the onset of fall and winter and winter and spring. Some patients have rhythmic epigastric pain associated with meals, hunger pain or night pain, relieved by meals; abdominal pain can be relieved by acid-suppressing drugs or antacids. 2. Dyspepsia: patients may have symptoms of dyspepsia such as epigastric distension, epigastric discomfort, anorexia, warmth and acid reflux. 3. Other: some patients may have weight loss, constipation, diarrhea and so on. Some patients with chronic blood loss due to ulcers may develop anemia manifestations such as fatigue, dizziness and pallor. There is also a class of asymptomatic ulcers, these patients do not have abdominal pain or dyspeptic symptoms, and the first symptom of gastrointestinal bleeding, perforation and other complications. They can be seen at any age, and are more common in patients who have been taking NSAIDs for a long time and in the elderly. Once the epigastric pain and discomfort, acid reflux, belching and other symptoms, should consult a doctor in time to clarify the cause of the disease, and then follow the doctor’s instructions for treatment.